XV. Spices

XV. 31 Other classic spices (sumac, bay leaf, dill, tarragon)

Four classic spices in a brief catalog – Middle Eastern sumac, Mediterranean bay leaf, Hungarian dill, French tarragon.

Function: Brief catalog of 4 classic spicesEvidence: ★★ (variable)Microbiota: indirect polyphenol and essential-oil matricesSource: EMA/HMPC monographs + peer-reviewed RCTs (variable)
🎯 What does this chapter cover?

This chapter presents four classic spices in a brief, compact format – each with limited human evidence that does not justify a standalone main chapter, but together they are valuable elements of Mediterranean–Middle Eastern–Hungarian culinary culture. Each detailed description follows the standard chapter structure in miniaturized form.

🍋 Sumac (Rhus coriaria)

Origin: Middle East, Levant, eastern coast of the Mediterranean. One of the main components of the classic Lebanese "za'atar" blend. Ground berries of the tanner-tree family (Anacardiaceae) give a tangy-sour, lemony-flavored powder.

Bioactive profile: Hydrolyzable tannin (gallotannin) 5–15%, anthocyanins (cyanidin glucoside), quercetin, kaempferol, high vitamin C [2894]. The ORAC value is among the highest of all spices (Vyas 2024 Foods review ).

Clinical evidence: Mohammadi Pour 2019 Phytother Res meta-analysis: sumac 3 g/day for 4–12 weeks – significant blood-sugar reduction (HbA1c −0.5%) in T2D patients. Shidfar 2014 J Res Med Sci [2885] showed lipid modulation.

Use: sprinkled on salad (classic "fattoush"), on hummus, on roasted meat, on eggplant. The natural alternative to lemon in eastern Mediterranean cuisine.

Microbiome aspect: indirect polyphenol-tannin matrix with Akkermansia/Lactobacillus support potentially, without human microbiome RCT evidence.

FODMAP: low. Contraindication: close relative of the toxic Rhus toxicodendron (poison ivy) – only from verified sources. Aspirin sensitivity (sumac contains salicylates).

🌿 Bay leaf (Laurus nobilis)

Origin: Mediterranean. The classic "garni" bundle of Greek-Roman cuisine. An essential element of the French "bouquet garni" for soups and stews. Hungarian culinary classic.

Bioactive profile: 1,8-cineole (eucalyptol, 30–50% in the essential oil), linalool, sabinene, α-pinene; quercetin and kaempferol glycosides; fiber.

Clinical evidence: Khan 2009 Eur J Clin Nutr [2438] – diabetes RCT with 1–3 g bay leaf/day for 30 days: significant improvement in blood sugar, lipids, and insulin sensitivity in T2D patients. As a spice alone it is not a clinical dose; in capsule or tea form it is meaningful.

Use: for flavoring soups, stews, marinades – during cooking, before consuming the leaf is removed (bloating, allergen risk). The base spice of Hungarian goulash, paprikash, and sour soups.

Microbiome aspect: in vitro antimicrobial – moderate against Helicobacter pylori, Salmonella. Human microbiome RCT evidence is sparse.

FODMAP: green. Contraindication: the whole leaf is NOT eaten – sharp, hard, GI-obstruction risk (especially dangerous for children). Diabetes with insulin pump: bay-leaf tea/capsule can cause hypoglycemia – monitor drug dosing [2887].

🌱 Dill (Anethum graveolens)

Origin: Mediterranean origin, but a classic element of Hungarian, Polish, Russian, and Scandinavian cuisines. The basis of the classic Hungarian "dill curd noodles" and "dill cucumber soup."

Bioactive profile: carvone and limonene (essential oil 60–80%), anethole, quercetin, kaempferol; vitamin A (beta-carotene), vitamin C, magnesium.

Clinical evidence: Sahib 2013 Asian Pac J Trop Biomed [2888] – dill extract (kapsa) brought lipid-profile improvement in a small human pilot. Hosseinzadeh 2002 J Ethnopharmacol documented preclinically the traditional antispasmodic claim. Clinical human RCT evidence is modest.

Use: in fresh salad, yogurt-tzatziki, with fish (classic Scandinavian "gravlax"), cucumber salad, fermented pickles. Long cooking removes its aroma – add at the END of cooking.

Microbiome aspect: indirect antimicrobial in vitro; no specific human evidence [2889].

FODMAP: green. Contraindication: rare allergy (Apiaceae family cross-reactivity: celery, carrot, anise). High-dose essential-oil capsule to be avoided in pregnancy (uterotonic potential, weak evidence) [2890].

🌾 Tarragon (Artemisia dracunculus)

Origin: Central Asian origin, but an iconic member of the classic French "fines herbes" blend. In Hungarian cuisine – especially the Transylvanian and Upper Hungarian tradition – the basis of the classic "tarragon soup."

Bioactive profile: "French tarragon" (A. dracunculus sativa) has high estragole (60–80% of essential oil), high linalool. "Russian tarragon" (A. dracunculus inodora) has substantially lower estragole content, weaker flavor, safer. Quercetin, kaempferol, rutin in the polyphenol fraction.

Clinical evidence: Méndez-del Villar 2016 J Med Food – tarragon extract (Tarralin®) 1000 mg/day, 90 days, in prediabetic patients: significant improvement in blood sugar and insulin sensitivity. Clinical human evidence is at low dose, with few RCTs.

Use: chicken, fish, egg dishes, sauces (béarnaise!), salad dressings, classic "tarragon chicken soup." Fresh tarragon gives maximum aroma with brief cooking.

Microbiome aspect: no direct human evidence; moderate in vitro antimicrobial.

FODMAP: green. Contraindication – CRITICAL: estragole is genotoxic + carcinogenic in animal models (EFSA 2009 assessment [2892]). High-dose supplement long-term TO BE AVOIDED [2893]. Dietary spice amount (1–2 g fresh, 0.5 g dried) is safe. High-dose capsule to be avoided in pregnancy.

References

[2438] Khan A et al. Bay leaves improve glucose and lipid profile of people with type 2 diabetes2009;44(1):52–56. J Clin Biochem Nutr. 2009. Link

Bay leaves (Laurus nobilis) have been shown to improve insulin function in vitro but the effects on people have not been determined. The objective of this study was to determine if bay leaves may be important in the prevention and/or alleviation of type 2 diabetes. Forty people with type 2 diabetes were divided into 4 groups and given capsules containing 1, 2 or 3 g of ground bay leaves per day for 30 days or a placebo followed by a 10 day washout period. All three levels of bay leaves reduced serum glucose with significant decreases ranging from 21 to 26\% after 30 d. Total cholesterol decreased, 20 to 24\%, after 30 days with larger decreases in low density lipoprotein (LDL) cholesterol of 32 to 40\%. High density lipoprotein (HDL) cholesterol increased 29 and 20\% in the groups receiving 1 and 2 g of bay leaves, respectively.

[2885] Rahideh ST, Shidfar F, Khandozi N, Rajab A, Hosseini SP, Mirtaher SM. The effect of sumac (Rhus coriaria L.) powder on insulin resistance, malondialdehyde, high sensitive C-reactive protein and paraoxonase 1 activity in type 2 diabetic patients. Journal of Research in Medical Sciences. 2014. Link

Double-blind, placebo-controlled RCT (41 type 2 diabetic patients) on the effect of sumac (Rhus coriaria) powder on insulin resistance, malondialdehyde, hsCRP and paraoxonase 1 activity; showed improvement in inflammatory and oxidative-stress markers. Clinical evidence for the metabolic effect of sumac. (Record verified via PubMed: J Res Med Sci 2014;19(10):933–938, PMID 25538775, PMC4274568 — no DOI assigned; the chapter's original title and "lipid profile" framing were imprecise, the actual endpoints are insulin resistance and hsCRP.)

[2887] . Laurus nobilis L., folium — assessment report. European Medicines Agency — Committee on Herbal Medicinal Products. 2017. Link

EMA/HMPC assessment report on bay leaf (Laurus nobilis, folium): traditional use, composition, safety. A regulatory safety reference for bay leaf. (Regulatory database source, not a peer-reviewed article; the URL points to the EMA Laurus nobilis, folium herbal-product page.)

[2888] Sahib AS, Mohammad IH, AlGareeb AI. Effects of Anethum graveolens leave powder on lipid profile in hyperlipidemic patients. Spatula DD. 2012. Link

Human study: dill (Anethum graveolens) leaf powder produced significant lipid-profile improvement (reductions in total cholesterol, triglycerides, LDL) in hyperlipidemic patients, comparable to lovastatin. Clinical background for the lipid effect of dill. (Record verified via Crossref: Spatula DD 2012;2(3):153–158, DOI 10.5455/spatula.20120907123553; the chapter's original Asian Pac J Trop Biomed 2013 citation was incorrect — the correct journal is Spatula DD, year 2012.)

[2889] Jana S, Shekhawat GS. Anethum graveolens: an Indian traditional medicinal herb — review. Pharmacognosy Reviews. 2010. Link

Review of dill (Anethum graveolens) as a traditional medicinal herb: composition, traditional use, antimicrobial and antispasmodic properties. A background reference for the dill profile. (Record verified via PubMed/Crossref: Pharmacogn Rev 2010;4(8):179–184, DOI 10.4103/0973-7847.70915, PMID 22228959.)

[2890] . Anethum graveolens L., fructus — herbal monograph. European Medicines Agency — Committee on Herbal Medicinal Products. 2015. Link

EMA/HMPC European Union herbal monograph on dill fruit (Anethum graveolens, fructus): traditional use, dosing, safety (pregnancy warning). A regulatory safety reference. (Regulatory database source, not a peer-reviewed article; the URL points to the EMA Anethi fructus herbal-product page.)

[2892] . Compendium of botanicals reported to contain naturally occurring substances of possible concern for human health — estragole assessment. EFSA Journal. 2009. Link

EFSA "Compendium of botanicals" (2009) listing plants reported to contain substances of concern; Artemisia dracunculus (tarragon) is listed among estragole-containing plants — the precautionary basis for avoiding long-term high-dose supplements. (Regulatory source verified via Crossref: EFSA Journal 2009;7(9):281, DOI 10.2903/j.efsa.2009.281.)

[2893] . Artemisia dracunculus L., herba — herbal monograph (preliminary). European Medicines Agency — Committee on Herbal Medicinal Products. 2018. Link

EMA/HMPC preliminary herbal monograph on the aerial parts of tarragon (Artemisia dracunculus, herba): traditional use and safety considerations. A regulatory reference. (Note: the stated URL points only to EMA's general herbal-medicines listing, not to a specific Artemisia dracunculus document; the existence/title of the specific EMA record is pending verification.)

[2894] . Sumac, bay leaves, dill, and tarragon — nutrient profiles (NDB #02038, #02004, #02045, #02064). USDA FoodData Central. 2019. Link

USDA FoodData Central entries for the macro- and micronutrient composition of sumac, bay leaves, dill, and tarragon. A reference source for the nutrient values reported in the chapter.

Authors:
PG
Dr. Patay Gábor
physician, microbiota specialist
BA
Dr. Bezzegh Attila
medical director, clinical microbiologist
AM
Dra. Anna Munar
physician, exposome specialist
MicroBiome Bank — medically reviewed professional content. Last updated: 2026.